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ONCE Dialyze

Medical food for dialysis patients

Once Dialyze powder consists of protein, fat, carbohydrate, vitamin and mineral for supplement the meal. Optimum for dialysis patients who need to control electrolyte limit, water and mineral balance.

FORMULA FOR DIALYSIS STAGE

• High protein which suitable for dialysis patient.
• Good quality of protein from whey protein isolate and casein.
• Vitamin A, Sodium, Potassium and Phosporus that optimum for dialysis patients.
• High energy
• Contains Isomaltulose, Fibersol-2 and Fructooligosaccharide.
• No sucrose added, Lactose free.

Vanilla flavor

Description

• Caloric distribution from 18% protein, 42% carbohydrate, 40% fat
• Supplement for daily meal
• Consists of whey protein isolate and casein; contributes to a source of essential amino acids for body protein synthesis
• Contains Canola oil, High oleic acid-safflower oil, Rice bran oil and MCT oil as source of energy.
• Contains dietary fiber; contributes to an increase in fecal bulk and stimulates the bowel movement.

Food advertising no.1544/2565
Net weight 400 grams

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Nutrition Fact

Nutrients

Per 80 g Per 1000 kcal Percent amount compared to RNI suggested by WHO (*) per 80 g powder Percent amount compared to THAI RDI (***) per 80 g powder

Energy, kcal

370.0

1,000

**

18.50

Protein, g

16.98

45.89

**

33.96

Carbohydrate, g

41.19

111.3

**

13.73

Fat, g

16.45

44.46

**

25.31

Dietary fiber, g

5.00

13.51

**

20.00

Vitamin A, IU

70.38

190.2

4

2..64

Vitamin D, IU

3.20

8.65

1-2

1.60

Vitamin E, IU

4.58

12.38

31-41

30.70

Vitamin C, mg

37.48

101.3

83

62.47

Vitamin B1, mg

0.38

1.03

32-35

25.33

Vitamin B2, mg

0.32

0.86

25-29

18.82

Vitamin B6, mg

2.50

6.76

147-192

125.0

Vitamin B12, mcg

4.50

12.16

188

225.0

Pantothenic acid, mg

1.50

4.05

30

25.00

Niacin, mg

3.75

10.14

23-27

18.75

Folic acid, mcg

255.3

690.0

106

212.8

Biotin, mcg

14.99

40.51

50

9.99

Vitamin K1, mcg

15.00

40.54

23-27

18.75

Choline, mg

120.0

324.3

**

****

Calcium, mg

149.9

405.1

12-15

18.74

Phosphorus, mg

149.9

405.1

**

18.74

Magnesium, mg

40.82

110.3

16-19

11.66

Sodium, mg

154.4

417.3

**

7.72

Potassium, mg

206.2

557.3

**

5.89

Chloride, mg

132.2

357.3

**

3.89

Iron, mg

2.81

7.59

10-25

18.73

Zinc, mg

3.74

10.11

53-76

24.93

Copper, mg

0.21

0.57

**

10.50

Manganese, mg

0.66

1.78

**

18.86

Iodine, mcg

28.14

76.05

19

18.76

Carnitine, mg

104.1

281.4

**

****

Chromium, mcg

24.36

65.84

**

18.74

Selenium, mcg

13.12

35.46

39-50

18.74

Molybdenum, mcg

18.74

50.65

**

11.71

Taurine, mg

27.91

75.43

**

****

(*) % of nutrients compared to recommended nutrient intake according to WHO criteria

(**) daily amount not established by WHO

(***) THAI RDI = Thai recommended daily intake for ages of 6 years and up

(****) daily amount not established by THAI RDI

Food advertising no.1544/2565

Main Composition

Main composition in approximate %w/w
Isomaltulose

28.11

Maltodextrin

17.01

Calcium caseniate

9.47

Sodium caseniate

7.18

Whey protein isolate

6.94

MCT oil

6.56

Rice bran oil

6.50

Canola oil

5.00

Fructooligosaccharide

3.44

Fibersol-2

2.81

High oleic safflower oil

2.50

Total minerals

1.18

Vanilla, Milk and Honey flavour

(Nature identical flavor)

0.43

Total Vitamins

0.08

Food advertising no.1544/2565

Food Allergy

Contains protein from milk

Remark

  • Food serial no. 74-1-21431-5-0004
  • Manufacturer is certified HACCP for enteral nutrition products by SGS (Thailand) Limited
  • Registration No. CICOT. HL. 99 B533 012 03 63
  • Manufactured by: Thai Otsuka Pharmaceutical Co., Ltd 50, Sethakij 1 Road, Khlong Madua Kra Tum Ban, Samutsakorn, Thailand

Date of manufacture and expiry, see bottom of can

Food advertising no.1544/2565

Preparation

80 grams of ONCE Dialyze (5 spoons) dissolved in 190 mL water (room temperature, lukewarm or cool water and adjust with water to final volume of 250 mL (approximate 370 Kilocalories).

5 spoon (80 grams) + 190 mL of water = 250 mL (370 Kilocalories)

Storage

  • After mixing with water, the prepared solution should be consumed immediately or kept in the refrigerator (2-8°C) with the closed container and should be consumed within 24 hours.
  • Close the container tightly after opened and keep in dry place and the product should be consumed within 1 month.

Recommendation for use

  • Use under medical supervision for supplement in daily meal of dialysis patients.
  • Suspension and precipitation can happen after preparation, the prepared solution can be homogeneous again by shaking or stirring gently.
  • Intravenous administration is prohibited.

Medical food must be used under medical supervision.

Food advertising no.1544/2565

Related Research

Purpose
To study changes in nutritional status and safety in dialysis patients undergoing peritoneal dialysis after receiving ONCE Dialyze
- Primary outcome: nutritional assessment with body weight measurement, Prealbumin and with Modified Subjective Global Assessment
- Secondary outcome: Safety Assessment by gastrointestinal side effects, mineral levels (Electrolyte level)

Methodology
This was a pre-post treatment comparative study (open-label) to determine whether ONCE Dialyze was taken as dietary supplement adding one meal for 15 days in 33 peritoneal dialysis patients at Phramongkutklao Hospital and Chaiyaphum Hospital.

Results
-After receiving ONCE Dialyze for 15 days, patients' nutritional intake (energy, protein, carbs, fat, fiber, potassium, calcium, and magnesium) increased considerably
- Patients who took part in the study showed improved nutritional status. After receiving ONCE Dialyze, the modified SGA score reduced from 24.2 % to 18.2 % (6 % reduction), which was consistent with serum pre-albumin levels and significantlt increased patient's body weight.
- Product safety: There was no evidence of hyperkalemia. High blood calcium and phosphate levels were statistically significant, and none of the subjects in the study experienced any side effects. or have been admitted to a hospital, or have died.

Summary of the study
As ONCE Dialyze is given to people on dialysis who have chronic renal disease as dietary supplement with a typical meal, the patient's nutritional intake including energy, protein, carbohydrate, fat, and fiber was increased, and electrolyte was at proper level. Additionally, it improved the malnutrition condition by the modified SGA score.  Dietary supplement intake for particular disease is an efficient method to increase nutrition for those on dialysis who have chronic kidney disease.

Product Mixing Table

Concentration and volume (1 g = 4.63 kcal, 1 spoon = 16 g)
Concentration (kcal / mL)  

0.5

1.0

Powder

Volume Powder

Mix with Water

Energy

Powder

Volume Powder

Mix with Water

Energy

(g)

(spoon)

(mL)

(kcal)

(g)

(spoon)

(mL)

(kcal)

10.8

0.7

100

50

21.6

1.4

100

100

16.2

1.0

150

75

32.4

2.0

150

150

21.6

1.4

200

100

43.2

2.7

200

200

27.0

1.7

250

125

54.1

3.4

250

250

32.4

2.0

300

150

64.9

4.1

300

300

37.8

2.4

350

175

75.7

4.7

350

350

43.2

2.7

400

200

86.5

5.4

400

400

48.6

3.0

450

225

97.3

6.1

450

450

54.1

3.4

500

250

108.1

6.8

500

500

108.1

6.8

1,000

500

216.2

13.5

1,000

1,000

129.7

8.1

1,200

600

259.5

16.2

1,200

1,200

162.2

10.1

1,500

750

324.3

20.3

1,500

1,500

194.6

12.2

1,800

900

389.2

24.3

1,800

1,800

216.2

13.5

2,000

1,000

432.4

27.0

2,000

2,000